Computer models that use "functional economic areas" framework of regional modelling
Any subnational economic modeling includes two challenging components: data and structure. Detailed subnational data for the US is automatically suspect because input-output tables are not collected at any subnational level. Interstate (domestic) trade is also a problem. (A small price to pay for the interstate-commerce clause: no state or municipal-level customs clearance => no data). The Commodity Flow Survey is the only source for domestic trade and there are significant problems with these data. They are not designed to measure source-destination trade a